Precision Capturing® Technology

Non-Antibody and Antibody Purification

In conventional biologics production, sequential multi-step downstream chromatography procedures impact, more than any other factor, overall manufacturing costs, process development and manufacturing timelines. Additionally, they pose a continuing manufacturing risk and require a different downstream process (DSP) for each new biologic.

Navigo Proteins’ Precision Capturing® technology dramatically simplifies non-Fc biologics downstream processing from pre-clinical stage to commercial manufacturing. This is achieved by substituting several chromatography steps by one single custom affinity chromatography capture step based on Navigo’s proprietary artificial Protein A affinity ligands. Downstream process development and manufacturing timelines are effectively shortened while yields, process robustness and product quality are optimized.

Precision Capturing® delivers next-generation downstream processing solutions for all biological product classes, including antibodies, fusion proteins, enzymes, hormones, blood factors, as well as vaccines, viral vectors, virus-like particles, or even entire cells.

Navigo Proteins® provides end-to-end affinity chromatography solutions from ligand discovery up to large scale resin supplies for commercial biologics manufacturing. Established reliable partnerships with renowned, global bioprocessing companies rapidly convert Precision Capturing® ligands into commercially available, ready-to-use affinity chromatography solutions for industrial, GMP-compliant biologics downstream processing.

Custom Affinity Chromatography using Precision Capturing® Ligands